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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDX1
All Species:
31.21
Human Site:
Y37
Identified Species:
62.42
UniProt:
P52945
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52945
NP_000200.1
283
30771
Y37
A
S
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Chimpanzee
Pan troglodytes
A2T756
283
30712
Y37
A
G
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001096758
281
30575
Y37
A
S
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Dog
Lupus familis
XP_543155
532
56855
Y287
A
S
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
P52946
284
30981
Y37
A
N
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Rat
Rattus norvegicus
P52947
283
30812
Y37
A
N
P
P
A
C
L
Y
M
G
R
Q
P
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519548
259
28495
Y37
P
S
P
P
A
C
L
Y
M
G
R
H
P
P
P
Chicken
Gallus gallus
XP_001234636
231
26345
G37
P
P
A
C
L
Y
V
G
R
Q
Q
Q
A
P
Y
Frog
Xenopus laevis
P14837
271
31388
Y37
P
S
P
P
A
C
L
Y
M
G
R
Q
Q
Q
A
Zebra Danio
Brachydanio rerio
O42370
396
43083
E85
S
Q
P
E
S
I
S
E
Q
Q
Q
A
A
P
L
Tiger Blowfish
Takifugu rubipres
Q1KKS7
408
44369
S100
S
S
P
S
P
N
S
S
S
S
Q
K
K
K
S
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999815
390
43430
A103
Q
D
L
S
R
P
L
A
L
A
Q
Q
A
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.2
49.6
N.A.
87.6
88.6
N.A.
64.3
63.2
57.9
26.7
26.9
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
99.2
98.5
50
N.A.
89.4
90.1
N.A.
71
70.6
66.7
36.6
36.7
N.A.
N.A.
N.A.
44.1
P-Site Identity:
100
93.3
100
100
N.A.
93.3
93.3
N.A.
86.6
13.3
73.3
13.3
13.3
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
100
100
N.A.
100
100
N.A.
86.6
26.6
73.3
33.3
33.3
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
9
0
67
0
0
9
0
9
0
9
25
0
9
% A
% Cys:
0
0
0
9
0
67
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
9
0
67
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
9
9
9
0
% K
% Leu:
0
0
9
0
9
0
75
0
9
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
25
9
84
67
9
9
0
0
0
0
0
0
59
75
59
% P
% Gln:
9
9
0
0
0
0
0
0
9
17
34
75
9
9
0
% Q
% Arg:
0
0
0
0
9
0
0
0
9
0
67
0
0
0
0
% R
% Ser:
17
50
0
17
9
0
17
9
9
9
0
0
0
0
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
67
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _